The Premier Division's top two meet at Richmond Park as leaders St Patrick's Athletic host Bohemians, kick-off 8.00pm.
Both sides have been hit by injuries this term and it is more of the same for tonight.
Pat's will be without the injured trio of Joe O'Cearuill, John Frost and Michael Keane.
However, Johnny McDonnell does have Joseph Ndo, David Partridge and Stephen Paisley available once again after a mixture of injury, and in Paisley's case, suspension.
Pat's return to Richmond Park after difficult away trips to Drogheda United and Sligo Rovers and McDonnell is pleased to come back to Inchicore.
He said: 'We had two tough away games at Drogheda and Sligo so we're delighted to be back playing at Richmond with a full house behind us. It's also great to welcome players back from injury at this stage in the season.'
Pat's won the reverse fixture earlier this season in a heated encounter at Dalymount Park but McDonnell is full of praise for the way Bohs have got themselves back into the title race following that defeat.
'Bohs are having a great season. People point to the size of their squad but other teams in the league have big squads. It takes a lot of hard work to get to where they are, so we can expect the toughest of games'
Bohs will travel south across the Liffey without John Paul Kelly (knee), captain Kevin Hunt (toe) and Thomas Heary (knee). Pat Fenlon also has doubts over Stephen O'Donnell (toe), Conor Powell (ankle) and Glenn Cronin (groin).
Bohemians' only dropped points on their travels this season came in a 1-1 draw at UCD. Fenlon believes his side are in better form than they were when the sides first met and is hopeful of continuing their fine form away from Dalymount.
He said: 'We will be going to Inchicore to win. Richmond Park is a difficult venue but the pitch is in great condition and they have made it a little bigger so there will be more room to play.
'Pat's are the only team to beat us at home but we have improved a great deal since that game. I feel we are playing with more consistency at the moment and the players know what is expected of them.'
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