The first staging of this fixture earlier this season was one of the most entertaining matches so far, and this promises to be just as exciting.
The Super Saints finally have Joseph Ndo back fighting for a first-team place, while Stephen Paisley and David Partridge are back to give options in defence.
Michael Keane, John Frost, and Joe O'Ceaurill are all out injured, so manager John McDonnell will have to carefully consider what team to select for this one.
"Bohs are having a great season. It takes a lot of hard work to get to where they are so we can expect the toughest of games," said McDonnell.
Pat Fenlon will bring a depleted Bohemians side across the River Liffey for this match as a number of players are carrying knocks.
John Paul Kelly, Glenn Cronin, Stephen O'Donnell, and Conor Powell are all doubts going into the match, so Chris Turner and Harpal Singh could earn rare starts.
The Gypsies will also have to decide what is the best strike partnership to go with as Neale Fenn, Glen Crowe, and Jason Byrne have all been rotating in recent games, and Darren Mansaram has hardly featured.
"St Pat's are a very good side and they have a lot of quality players. This will be a very difficult game for us and we will have to be at our best to take something from Inchicore," said Fenlon.
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